51ÁÔÆæ

Self-Testing for Group B Streptococcus (GBS) Positive Status in Pregnancy

Some individuals are advised to have testing for Group B Strep (GBS) in their current pregnancyÌýbetween 35-37Ìýweeks:Ìý

  • You were identified to have had a positive GBSÌýresultÌýin a previous pregnancyÌýÌý
  • A previous baby was diagnosed and treatedÌýfor GBS Positive resultÌýÌý
  • GBS was identified by chance earlier in your pregnancyÌýeither in your urine or from a swabÌýand you are being offered a repeat testÌý

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A Brief Summary of What is GBS and Why test for it?ÌýÌý

Group B StreptococcusÌý(GBS)Ìýis normally a harmless andÌýcommon bacteriaÌýwhich may be identified in your urine or from aÌývaginalÌýand/or rectal swab, it effectsÌý2–4 in 10 women (20–40%) in the UKÌýand usually causes no harm to that individual, there are no symptoms and it is not a sexually transmitted infection.ÌýÌý

Whilst carrying GBS is usuallyÌýharmlessÌýpre-pregnancy or during pregnancy,Ìýit mayÌýaffect your baby around the time of birth.ÌýWhilst most babies are born safely and will not developÌýGBS,ÌýoccasionallyÌýit can causeÌýserious infection in newborn babies.Ìý

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When and how do you test for GBS?ÌýÌý

Routine testing of all pregnant individualsÌýis notÌýgenerallyÌýrecommended in the UKÌýas GBS is a transient organismÌý(can come and go),ÌýscreeningÌýis currently based upon risk factorsÌýas stated above.Ìý

Where individualsÌýchoose to undertake the test, this is normally recommended between 35-37 weeks gestation (32-34 weeks for twins).ÌýThe test involves taking a swab from both the lower vaginalÌýand anal/rectal areasÌý(see below), and thisÌýtest will tell you if GBS bacteria is currently present at that time of testing.ÌýÌý

For more information about availableÌýself-testing, not through the NHS, visit the Group B Strep Support (GBSS) website:ÌýÌýÌý

Sometime GBS can be detected by chance in aÌýurine sample,Ìýwhen a healthcare professionalÌýsends a sample off for screening for a suspected urinary tract infection. If this is detected in your urine, oral antibiotics will beÌýadvisedÌýand you will be offeredÌýintravenous (IV)Ìýprophylactic antibiotics in labour.ÌýÌý

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Instructions for the collection of a low vaginal and anorectal swab for the detection of Group B Streptococcus (GBS)Ìý

You will have been provided with a swab to undertake self-testing procedure to determine if you have a current presence of the group B Streptococcus (GBS) bacterium present within your vagina or bowel. Please read all instructions before collecting specimens. If you have any questions about this procedure, please ask your midwife or doctor.Ìý

  1. Wash hands with soap and water, rinse and dry.Ìý
  2. Unpack the kit on a clean surface, ideally near a toilet and remove underwear.Ìý
  3. It is important to maintain a comfortable balance during the collection procedure.Ìý
  4. Twist the cap to break the seal of the swab. Pull the cap with attached swab off the tube. Do not touch the soft tip or lay the swab down. If you touch or drop the swab tip or the swab is laid down, discard and request a new vaginal swab from your midwife.Ìý
  5. Hold the swabÌýbyÌýthe cap with one hand so the swab is pointing toward you.Ìý
  6. With your other hand, gently spread the skin of the labia. Insert the tip of the swab into the vaginal opening. Point the tip toward your lower back and relax your muscles.Ìý
  7. Gently slide the swabÌýaroundÌý2cm into the vagina. If the swab does not slide easily, gently rotate the swab as you push. If it is still difficult, do not attempt to continue and seek advice from your midwife.Ìý
  8. Make sure the swab touches the inside walls of the vagina so that moisture is absorbed.Ìý
  9. Rotate the swab for 10-15 secondsÌýaround the front, sides and back of the vaginaÌýand then withdraw the swab.Ìý
  10. InsertÌýthe same swabÌýgently into the anus so that around 1cm of the swab is within the rectum.Ìý
  11. Rotate the swab for 10-15 seconds and then withdraw the swab.Ìý
  12. Return the swab to the tube and cap securely.Ìý
  13. AfterÌýcollection, wash hands with soap and water, rinse and dry.Ìý
  14. Apply a patient ID label from the request from to the side of the tube and seal within a transport bag. Return the sample with the request form to your midwife or doctor.Ìý

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How toÌýstore the sample if done at home and not in the hospital or during a community midwifeÌýappointment.ÌýÌý

Ideally, you should deliver the sample to Antenatal Clinic reception, MAC or Delivery Suite as soon as possible after the sample has been taken. If you cannot deliver the sample immediately it should be stored in a fridge at around 4°C, but for no longer than 24 hours. Place the sample in an extra plastic bag before putting it in the fridge.Ìý

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What happens next?Ìý

The sample will be tested at the pathology department at 51ÁÔÆæ District Hospital. Your results will normally be reported within 72 hours after the pathology department has received your sample.Ìý

Results will be checked by your midwife orÌýdoctorÌýand we will contact you if the test results suggest further action is needed. Normally, no treatment will be required until presenting in labour.ÌýIf you have been informedÌýof a GBS positive result,Ìýit is important that you make staff aware of this when contacting the maternity unit, if your waters break, if you feel unwell or when presenting in labour.Ìý

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What happens to my sample after it has been tested?Ìý

Once your sample has been tested and a result has been sent back to your referring doctor or midwife, the remaining sample will be disposed of with the other laboratory waste.Ìý

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What does the test result mean?ÌýÌý

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If your result is GBS NegativeÌýÌý

This means that the test has not managed to isolate the organism and it is likely that you do not currently have GBS within your vagina or bowel. NoÌýfurther action is required and there should be noÌýchange to your labour management.ÌýÌý

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If your result is GBS PositiveÌýÌý

This means that GBS has been found withinÌýyour vagina or bowel. ThereÌýis a small chanceÌýof this being passed to your baby during the birth, andÌýyou are recommended to have antibiotics in labourÌýto reduce the risk of transmission.ÌýÌý

Antibiotics reduce the risk of your baby developing a GBS infection in their first week of life from around 1 in 400 to 1 in 4000.ÌýIdeally antibioticsÌý(penicillin, or suitable alternative if you are allergic)Ìýshould be givenÌýat least 4 hours before your baby is bornÌýand would normallyÌýbeÌýadministeredÌýintravenously through a cannulaÌýin your hand everyÌý4Ìýhours throughout labour.ÌýIn addition:Ìý

  • ifÌýyour waters break (membranes rupture) prior to spontaneous labour you will be advisedÌýto have labour induced (artificially started) as soon as possible,Ìýas this is when the baby is at most risk of developing infection. Ask for ourÌý‘Induction of Labour’Ìýleaflet for more information.ÌýÌý
  • youÌýare still eligible to use the bath for labour and birthÌý(unless you have other risk factorsÌýor need a hormone drip as part of the induction process)ÌýÌý
  • yourÌýbaby will be closely monitored for signsÌýof infection after birthÌý

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If your waters break preterm (before 37 weeks) but you are not in labour, you may be offered a course ofÌýoralÌýantibiotics.ÌýSee the National Institute of Health and Care Excellence (NICE) guidance NG25 on Preterm Labour and Birth:ÌýÌýÌý

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For more in-depth information regarding GBS pleaseÌýsee ‘Group B Streptococcus in Pregnancy and Newborn Babies’ leaflet (RCOG,ÌýÌýto read inÌýaddition to this page. Ìý

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ReferencesÌý

Group B Streptococcal Disease, Early Onset (Green Top Guideline No.36).ÌýÌý

Group B Streptococcus (GBS) in pregnancy and newborn babies. Information leaflet.ÌýÌý

Group B Strep Support (GBSS) website:ÌýÌýÌý

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National Institute of Health and Care Excellence (NICE) guidance NG25 on Preterm Labour and Birth:ÌýÌýÌý